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KMID : 1143620170210010054
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Korean Journal of Nuclear Medicine Technology
2017 Volume.21 No. 1 p.54 ~ p.59
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Comparison and Evaluation of the Effectiveness between Respiratory Gating Method Applying The Flow Mode and Additional Gated Method in PET/CT Scanning
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Jang Dong-Hoon
Kim Kyung-Hun
Lee Jin-Hyung
Cho Hyun-Duk
Park So-Hyun
Park Young-Jae
Lee In-Won
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Abstract
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Purpos : The present study aimed at assessing the effectiveness of the respiratory gating method used in the flow mode and additional localized respiratory-gated imaging, which differs from the step and go method.
Materials and Method : Respiratory gated imaging was performed in the flow mode to twenty patients with lung cancer (10 patients with stable signals and 10 patients with unstable signals), who underwent PET/CT scanning of the torso using
Biograph mCT Flow PET/CT at Bundang Seoul University Hospital from June 2016 to September 2016. Additional images of the lungs were obtained by using the respiratory gating method. SUVmax, SUVmean, and Tumor Volume (cm3 ) of non-gating images, gating images, and additional lung gating images were found with Syngo,bia (Siemens, Germany). A paired t-test was performed with GraphPad Prism6, and changes in the width of the amplitude range were compared between the two types of gating images.
Result : The following results were obtained from all patients when the respiratory gating method was applied: SUVmax = 9.43 ± 3.93, SUVmean = 1.77 ± 0.89, and Tumor Volume = 4.17 ± 2.41 for the non-gating images, SUVmax = 10.08 ± 4.07, SUVmean = 1.75 ± 0.81, and Tumor Volume = 3.56 ± 2.11 for the gating images, and SUVmax = 10.86 ± 4.36, SUVmean = 1.77 ± 0.85, Tumor Volume = 3.36 ± 1.98 for the additional lung gating images. No statistically significant difference in the values of SUVmean was found between the non-gating and gating images, and between the gating and lung gating images (P>0.05). A significant difference in the values of SUVmax and Tumor Volume were found between the aforementioned groups (P<0.05). The width of the amplitude range was smaller for lung gating images than gating images for 12 from 20 patients (3 patients with stable signals, 9 patients with unstable signals).
Conclusio : In PET/CT scanning using the respiratory gating method in the flow mode, any lesion movements caused by
respiration were adjusted; therefore, more accurate measurements of SUVmax, and Tumor Volume could be obtained from the gating images than the non-gating images in this study. In addition, the width of the amplitude range decreased according to the stability of respiration to a more significant degree in the additional lung gating images than the gating images. We found that gating images provide information that is more useful for diagnosis than the one provided by non-gating images. For patients with irregular signals, it may be helpful to perform localized scanning additionally if time allows.
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KEYWORD
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Flow mode, Respiratory Gating Method, SUV max , Tumor Volume
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